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MSH3 protein (Yarrowia lipolytica) - STRING interaction network
"MSH3" - YALI0A09724p in Yarrowia lipolytica
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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MSH3YALI0A09724p; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary c [...] (990 aa)    
Predicted Functional Partners:
XP_504806.1
YALI0F00154p; Component of the post-replicative DNA mismatch repair system (MMR) (887 aa)
   
0.987
XP_502661.1
YALI0D10571p; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (264 aa)
     
  0.976
XP_501666.1
YALI0C10032p (656 aa)
 
  0.961
XP_503794.1
YALI0E10769p (893 aa)
   
  0.924
XP_501549.1
YALI0C07260p (524 aa)
   
  0.886
POL2
YALI0E26367p; DNA polymerase II participates in chromosomal DNA replication (2183 aa)
     
 
  0.878
XP_503837.1
YALI0E11869p (1375 aa)
     
 
  0.873
XP_503925.1
YALI0E14014p (546 aa)
   
  0.871
XP_503990.1
YALI0E15642p (589 aa)
     
  0.866
XP_505910.1
YALI0F26499p; Component of the post-replicative DNA mismatch repair system (MMR) (1149 aa)
   
 
 
0.863
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
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