STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DYS1Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. (346 aa)    
Predicted Functional Partners:
YALI0_C06886g
Eukaryotic translation initiation factor 5A.
   
 0.995
LIA1
Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
   
 0.907
YALI0_B11330g
YALI0B11330p; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 
 0.687
YALI0_F16335g
YALI0F16335p.
     
 0.671
YALI0_E20361g
YALI0E20361p.
   
 
 0.636
YALI0_E33143g
YALI0E33143p; Belongs to the spermidine/spermine synthase family.
  
 
 0.589
YALI0_D16643g
YALI0D16643p.
   
  
 0.566
YALI0_E07535g
Arginase; Belongs to the arginase family.
  
  
 0.525
YALI0_D26367g
YALI0D26367p.
   
  
 0.514
YALI0_B01760g
YALI0B01760p.
  
  
 0.498
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 284591
Other names: Y. lipolytica CLIB122, Yarrowia lipolytica CLIB122
Server load: low (34%) [HD]