STRINGSTRING
LIS1 protein (Yarrowia lipolytica) - STRING interaction network
"LIS1" - YALI0B00902p in Yarrowia lipolytica
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIS1YALI0B00902p; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck (437 aa)    
Predicted Functional Partners:
XP_500289.1
YALI0A20504p (941 aa)
       
  0.969
XP_505230.1
YALI0F10010p; Lipid hydrolase (816 aa)
         
    0.900
XP_504704.1
YALI0E32857p (3982 aa)
       
  0.879
XP_505624.1
YALI0F19514p (512 aa)
         
    0.800
XP_505701.1
YALI0F21263p (340 aa)
   
 
 
  0.758
XP_502155.1
YALI0C22858p (424 aa)
     
  0.757
XP_502418.1
YALI0D04807p (429 aa)
     
  0.754
set-2
YALI0E18260p; Histone methyltransferase that methylates histone H3 to form H3K36me. Involved in transcription elongation as well as in transcription repression (By similarity) (768 aa)
     
  0.744
SET1
YALI0B14883p; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation (1170 aa)
     
  0.730
XP_503664.1
YALI0E07491p (788 aa)
     
  0.729
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
Server load: low (12%) [HD]