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CCR4 protein (Yarrowia lipolytica) - STRING interaction network
"CCR4" - YALI0B15147p in Yarrowia lipolytica
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCR4YALI0B15147p; Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Ccr4 has 3’-5’ RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Discovered because of its role in the control of ADH2 gene expression. It is required for the expression of genes involved in non-fermentative growth (By similarity) (705 aa)    
Predicted Functional Partners:
XP_505772.1
YALI0F23045p (2017 aa)
     
  0.993
XP_500803.1
YALI0B12496p (464 aa)
     
  0.992
XP_504943.1
YALI0F03344p (278 aa)
     
  0.978
XP_501245.1
YALI0B22968p (247 aa)
     
  0.977
XP_503626.1
YALI0E06435p (626 aa)
     
  0.976
XP_504890.1
YALI0F02101p (495 aa)
     
  0.975
XP_500756.1
YALI0B11352p (1111 aa)
     
  0.936
PAB1
YALI0C00539p; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation t [...] (629 aa)
       
  0.884
XP_500351.1
YALI0B00616p (589 aa)
       
  0.883
XP_505175.1
ubiquitin-60S ribosomal protein L40 fusion protein (128 aa)
       
  0.832
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
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