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HSV2 protein (Yarrowia lipolytica) - STRING interaction network
"HSV2" - YALI0B15290p in Yarrowia lipolytica
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
HSV2YALI0B15290p; Involved in mitochondrial or peroxisomal functions and amino acid signaling pathways (359 aa)    
Predicted Functional Partners:
ATG7
YALI0C20119p; E1-like activating enzyme involved in the 2 ubiquitin- like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitoc [...] (598 aa)
     
 
  0.670
ATG2
YALI0E08338p; Required for cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes completion and peroxisome degradation (1525 aa)
     
 
  0.632
ATG15
YALI0F06358p; Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity) (549 aa)
       
 
  0.613
XP_502723.1
YALI0D11968p (434 aa)
       
 
  0.581
XP_501699.1
YALI0C10901p (296 aa)
       
      0.517
ATG9
YALI0F08349p; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum- specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required [...] (788 aa)
     
   
  0.486
XP_504716.1
YALI0E33165p (370 aa)
     
      0.463
XP_504539.2
YALI0E29161p (2031 aa)
     
   
  0.458
ATG4
YALI0A13277p; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Cleaves the C-terminal amino acid of ATG8 to reveal a C-terminal glycine. ATG8 ubiquitin-like activity requires the exposure of the glycine at the C-terminus for its conjugation to phosphatidylethano [...] (545 aa)
     
   
  0.445
ATG5
YALI0E24519p; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy). Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like con [...] (256 aa)
           
  0.441
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
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