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TIF1 protein (Yarrowia lipolytica) - STRING interaction network
"TIF1" - YALI0B20922p in Yarrowia lipolytica
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIF1YALI0B20922p; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5’-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity) (395 aa)    
Predicted Functional Partners:
XP_501450.1
YALI0C04620p (919 aa)
     
  0.992
XP_500756.1
YALI0B11352p (1111 aa)
   
  0.975
XP_503327.1
YALI0D26664p (194 aa)
     
  0.973
XP_504609.1
YALI0E30877p (452 aa)
   
  0.962
XP_503462.2
YALI0E02530p (120 aa)
     
  0.956
CWC2
YALI0F29073p; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the "nineteen complex" NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre- mRNA intron near the 5’ splice site during the activation and catalytic phases of the s [...] (382 aa)
   
  0.947
CWC22
YALI0D20790p; Involved in pre-mRNA splicing (954 aa)
     
  0.917
XP_503225.1
YALI0D24299p (255 aa)
     
  0.890
XP_499612.1
YALI0A00352p (842 aa)
   
  0.844
XP_500302.1
YALI0A20768p (950 aa)
   
  0.834
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
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