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PAB1 protein (Yarrowia lipolytica) - STRING interaction network
"PAB1" - YALI0C00539p in Yarrowia lipolytica
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAB1YALI0C00539p; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation t [...] (629 aa)    
Predicted Functional Partners:
XP_500633.1
YALI0B08250p (728 aa)
     
  0.978
XP_503225.1
YALI0D24299p (255 aa)
     
  0.972
XP_500029.1
YALI0A13101p (867 aa)
     
  0.953
XP_501257.1
YALI0B23232p (638 aa)
     
 
  0.942
XP_501048.1
YALI0B18238p (147 aa)
       
      0.915
XP_501450.1
YALI0C04620p (919 aa)
     
  0.908
XP_499862.1
YALI0A08077p (327 aa)
     
 
  0.896
CCR4
YALI0B15147p; Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Ccr4 has 3’-5’ RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Discovered because of its role in the control of ADH2 gene expression. It is required for the expression of genes involved in non-fermentative growth (By similarity) (705 aa)
       
  0.884
XP_504544.2
YALI0E29293p (170 aa)
     
  0.862
RNA14
YALI0D18612p; Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3’-end formation (806 aa)
     
 
  0.852
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
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