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KU70 protein (Yarrowia lipolytica) - STRING interaction network
"KU70" - YALI0C08701p in Yarrowia lipolytica
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KU70YALI0C08701p; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere mainten [...] (585 aa)    
Predicted Functional Partners:
KU80
YALI0E02068p; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere mainten [...] (726 aa)
     
  0.995
XP_500889.1
YALI0B14553p (701 aa)
     
  0.966
XP_502732.1
YALI0D12188p (940 aa)
     
  0.957
XP_506116.1
YALI0F31977p (1300 aa)
     
 
  0.945
XP_503990.1
YALI0E15642p (589 aa)
     
 
  0.937
XP_502852.1
YALI0D15246p (1292 aa)
     
  0.906
LIG4
YALI0D21384p; Involved in ds DNA break repair. Has a role in non- homologous integration (NHI) pathways where it is required in the final step of non-homologus end-joining (By similarity) (956 aa)
     
  0.883
TEL1
YALI0D03888p; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity) (2282 aa)
       
  0.880
XP_504628.1
YALI0E31273p (1000 aa)
     
  0.840
XP_505672.1
YALI0F20636p (1845 aa)
       
  0.838
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
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