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PNG1 protein (Yarrowia lipolytica) - STRING interaction network
"PNG1" - YALI0C23562p in Yarrowia lipolytica
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNG1YALI0C23562p; Specifically deglycosylates the denatured form of N- linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl- glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high- mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subs [...] (356 aa)    
Predicted Functional Partners:
XP_502899.1
YALI0D16401p (359 aa)
       
  0.973
XP_505175.1
ubiquitin-60S ribosomal protein L40 fusion protein (128 aa)
       
  0.865
XP_504128.2
YALI0E18986p (457 aa)
       
  0.833
XP_505222.1
ubiquitin-40S ribosomal protein S31 fusion protein (150 aa)
       
  0.782
XP_505319.1
YALI0F12155p (814 aa)
       
  0.717
XP_503446.1
YALI0E02134p (343 aa)
       
  0.701
XP_002143115.1
YALI0F18403p (77 aa)
       
  0.701
XP_504910.1
YALI0F02585p (436 aa)
       
  0.687
XP_504863.1
YALI0F01496p (104 aa)
 
   
 
  0.674
XP_505937.1
YALI0F27225p; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins (304 aa)
       
  0.649
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
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