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TEL1 protein (Yarrowia lipolytica) - STRING interaction network
"TEL1" - YALI0D03888p in Yarrowia lipolytica
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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TEL1YALI0D03888p; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity) (2282 aa)    
Predicted Functional Partners:
XP_505672.1
YALI0F20636p (1845 aa)
     
0.964
XP_500837.1
YALI0B13376p (580 aa)
     
  0.947
XP_503925.1
YALI0E14014p (546 aa)
     
  0.884
XP_500889.1
YALI0B14553p (701 aa)
     
  0.882
KU80
YALI0E02068p; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere mainten [...] (726 aa)
     
  0.881
KU70
YALI0C08701p; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere mainten [...] (585 aa)
       
  0.880
LIG4
YALI0D21384p; Involved in ds DNA break repair. Has a role in non- homologous integration (NHI) pathways where it is required in the final step of non-homologus end-joining (By similarity) (956 aa)
     
 
  0.873
XP_502852.1
YALI0D15246p (1292 aa)
     
  0.843
XP_505458.1
YALI0F15477p (329 aa)
       
  0.839
XP_503990.1
YALI0E15642p (589 aa)
     
  0.836
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
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