GLR1 protein (Yarrowia lipolytica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GLR1

Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. (470 aa)

Predicted Functional Partners:

TRR1

0.970

YALI0_C17831g

0.962

YALI0_F01496g

0.941

YALI0_D08690g

0.941

YALI0_F08195g

0.940

YALI0_A19426g

0.940

YALI0_E33517g

0.932

YALI0_C11363g

0.920

YALI0_C20669g

0.919

YALI0_E02310g

0.916

Your Current Organism:

Yarrowia lipolytica

NCBI taxonomy Id: 284591
Other names: Y. lipolytica CLIB122, Yarrowia lipolytica CLIB122

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GLR1	TRR1	Q6C5H4	Q6C7L4	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol.	Thioredoxin reductase.	0.970
GLR1	YALI0_A19426g	Q6C5H4	Q6CGH1	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol.	YALI0A19426p.	0.940
GLR1	YALI0_C11363g	Q6C5H4	Q6CC93	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol.	YALI0C11363p.	0.920
GLR1	YALI0_C17831g	Q6C5H4	Q6CBL1	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol.	Glutathione synthetase.	0.962
GLR1	YALI0_C20669g	Q6C5H4	Q6CBA5	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol.	YALI0C20669p.	0.919
GLR1	YALI0_D08690g	Q6C5H4	Q6C9S7	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.941
GLR1	YALI0_E02310g	Q6C5H4	Q6C7A8	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.916
GLR1	YALI0_E33517g	Q6C5H4	Q6C3M8	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol.	YALI0E33517p.	0.932
GLR1	YALI0_F01496g	Q6C5H4	Q6C399	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol.	Thioredoxin; Belongs to the thioredoxin family.	0.941
GLR1	YALI0_F08195g	Q6C5H4	Q6C2G0	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol.	YALI0F08195p.	0.940
TRR1	GLR1	Q6C7L4	Q6C5H4	Thioredoxin reductase.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol.	0.970
TRR1	YALI0_A19426g	Q6C7L4	Q6CGH1	Thioredoxin reductase.	YALI0A19426p.	0.785
TRR1	YALI0_D08690g	Q6C7L4	Q6C9S7	Thioredoxin reductase.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.400
TRR1	YALI0_E02310g	Q6C7L4	Q6C7A8	Thioredoxin reductase.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.851
TRR1	YALI0_F01496g	Q6C7L4	Q6C399	Thioredoxin reductase.	Thioredoxin; Belongs to the thioredoxin family.	0.778
TRR1	YALI0_F08195g	Q6C7L4	Q6C2G0	Thioredoxin reductase.	YALI0F08195p.	0.788
YALI0_A19426g	GLR1	Q6CGH1	Q6C5H4	YALI0A19426p.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol.	0.940
YALI0_A19426g	TRR1	Q6CGH1	Q6C7L4	YALI0A19426p.	Thioredoxin reductase.	0.785
YALI0_A19426g	YALI0_C11363g	Q6CGH1	Q6CC93	YALI0A19426p.	YALI0C11363p.	0.913
YALI0_A19426g	YALI0_C17831g	Q6CGH1	Q6CBL1	YALI0A19426p.	Glutathione synthetase.	0.906