STRINGSTRING
HIR1 protein (Yarrowia lipolytica) - STRING interaction network
"HIR1" - YALI0E20933p in Yarrowia lipolytica
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIR1YALI0E20933p; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle (1058 aa)    
Predicted Functional Partners:
ASF1
YALI0A01375p; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly (265 aa)
     
  0.986
HIR3
YALI0D11506p; Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation (1921 aa)
     
 
  0.944
XP_505557.1
YALI0F17908p (481 aa)
     
 
  0.941
XP_503737.1
YALI0E09493p (2186 aa)
       
      0.898
XP_502687.1
YALI0D11176p (1420 aa)
       
      0.883
HHT1
YALI0F25905p; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity) (139 aa)
       
 
  0.758
CSE4
YALI0B13508p; Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity) (150 aa)
       
 
  0.758
XP_500681.1
YALI0B09471p (331 aa)
 
 
        0.689
XP_504989.2
YALI0F04356p (1242 aa)
     
  0.672
XP_503455.1
YALI0E02332p (1028 aa)
     
  0.672
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
Server load: low (10%) [HD]