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SEC61 protein (Yarrowia lipolytica) - STRING interaction network
"SEC61" - YALI0E21912p in Yarrowia lipolytica
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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Experiments
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[Homology]
Score
SEC61YALI0E21912p; Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins and is essential for cell growth. It interacts with other membrane proteins required for protein translocation. Upon binding to SEC62/63 complex, secretory precursor polypeptides may engage SEC61 to begin membrane penetration event. A cycle of assembly and disassembly of SEC62/63 from SEC61 may govern the activity of the translocase (By similarity) (471 aa)    
Predicted Functional Partners:
SBH1
YALI0F08481p; Necessary for protein translocation in the endoplasmic reticulum (91 aa)
     
  0.997
XP_002143050.1
YALI0D08635p (68 aa)
     
  0.996
XP_500184.1
YALI0A17985p (649 aa)
     
  0.983
XP_502492.1
YALI0D06589p; Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains (505 aa)
     
  0.983
XP_504222.1
60S ribosomal protein L26 (128 aa)
   
  0.982
XP_505871.1
60S ribosomal protein L25 (141 aa)
   
  0.974
XP_502683.1
YALI0D11066p (351 aa)
     
 
  0.969
XP_500914.2
60S ribosomal protein L11 (172 aa)
   
  0.953
XP_500404.1
YALI0B01892p (297 aa)
   
  0.947
RPL17
60S ribosomal protein L17 (184 aa)
   
  0.935
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
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