STRINGSTRING
XP_504806.1 protein (Yarrowia lipolytica) - STRING interaction network
"XP_504806.1" - YALI0F00154p in Yarrowia lipolytica
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XP_504806.1YALI0F00154p; Component of the post-replicative DNA mismatch repair system (MMR) (887 aa)    
Predicted Functional Partners:
MSH3
YALI0A09724p; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary c [...] (990 aa)
   
0.987
XP_505910.1
YALI0F26499p; Component of the post-replicative DNA mismatch repair system (MMR) (1149 aa)
   
0.987
XP_503990.1
YALI0E15642p (589 aa)
     
  0.975
XP_502661.1
YALI0D10571p; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (264 aa)
     
  0.974
FEN1
YALI0F20042p; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome [...] (389 aa)
   
  0.971
XP_503925.1
YALI0E14014p (546 aa)
   
  0.967
XP_501666.1
YALI0C10032p (656 aa)
 
  0.963
POL2
YALI0E26367p; DNA polymerase II participates in chromosomal DNA replication (2183 aa)
     
 
  0.938
XP_503794.1
YALI0E10769p (893 aa)
   
  0.935
XP_503288.1
YALI0D25762p (370 aa)
       
 
  0.935
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
Server load: low (4%) [HD]