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SEC65 protein (Yarrowia lipolytica) - STRING interaction network
"SEC65" - YALI0F21505p in Yarrowia lipolytica
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEC65YALI0F21505p; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. It must be involved intimately in the translocation of a wide variety of protein substrates (By similarity) (310 aa)    
Predicted Functional Partners:
XP_501994.1
YALI0C18997p; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane (561 aa)
     
  0.973
XP_504767.1
YALI0E34309p; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane (602 aa)
     
  0.972
SRP54
YALI0F03839p; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein) (536 aa)
     
  0.967
XP_504122.1
YALI0E18854p (406 aa)
     
      0.764
XP_505175.1
ubiquitin-60S ribosomal protein L40 fusion protein (128 aa)
     
  0.650
XP_500223.1
YALI0A18942p (186 aa)
       
 
  0.607
XP_505848.1
40S ribosomal protein S8 (198 aa)
   
 
    0.562
NSA2
Ribosome biogenesis protein NSA2; Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity) (262 aa)
   
 
    0.544
XP_505785.1
YALI0F23375p (557 aa)
       
  0.541
SEC61
YALI0E21912p; Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins and is essential for cell growth. It interacts with other membrane proteins required for protein translocation. Upon binding to SEC62/63 complex, secretory precursor polypeptides may engage SEC61 to begin membrane penetration event. A cycle of assembly and disassembly of SEC62/63 from SEC61 may govern the activity of the translocase (By similarity) (471 aa)
         
  0.512
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
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