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DPH1 protein (Yarrowia lipolytica) - STRING interaction network
"DPH1" - YALI0F22055p in Yarrowia lipolytica
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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DPH1YALI0F22055p; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L- methionine to a histidine residue. Diphthamide is a post- translational modification of histidine which occurs in elongation factor 2 (By similarity) (439 aa)    
Predicted Functional Partners:
DPH2
YALI0A19954p; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L- methionine to a histidine residue. Diphthamide is a post- translational modification of histidine which occurs in elongation factor 2 (By similarity) (481 aa)
     
0.985
DPH3
YALI0F24981p; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L- methionine to a histidine residue. Diphthamide is a post- translational modification of histidine which occurs in elongation factor 2 (By similarity) (69 aa)
     
  0.932
XP_500302.1
YALI0A20768p (950 aa)
     
  0.930
XP_500274.1
YALI0A20152p (842 aa)
     
  0.930
XP_499612.1
YALI0A00352p (842 aa)
     
  0.930
DPH5
YALI0F17138p; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis (300 aa)
     
  0.713
MEF1
YALI0D07326p; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A- site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (764 aa)
     
  0.669
MEF2
YALI0C18557p; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation (802 aa)
     
  0.669
XP_502894.1
YALI0D16291p (1018 aa)
       
  0.660
DIM1
YALI0E00770p; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3’-end of 18S rRNA in the 40S particle (317 aa)
   
        0.487
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
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