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UBC2 protein (Yarrowia lipolytica) - STRING interaction network
"UBC2" - YALI0F26697p in Yarrowia lipolytica
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query proteins and first shell of interactors
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second shell of interactors
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filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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UBC2YALI0F26697p; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation (151 aa)    
Predicted Functional Partners:
RAD18
YALI0A08580p; E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA (By similarity) (344 aa)
       
  0.986
XP_505175.1
ubiquitin-60S ribosomal protein L40 fusion protein (128 aa)
       
  0.978
XP_500468.1
YALI0B03718p (1877 aa)
     
  0.974
BRE1
YALI0B09559p; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation (By similarity) (700 aa)
     
 
  0.950
XP_503611.1
YALI0E06017p (1015 aa)
     
  0.938
XP_503583.1
YALI0E05401p (1497 aa)
     
  0.908
XP_500551.2
YALI0B05940p (3277 aa)
     
  0.896
XP_499961.1
YALI0A10879p (162 aa)
     
  0.871
UBA4
YALI0C18095p; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl- adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond [...] (396 aa)
       
  0.863
XP_504128.2
YALI0E18986p (457 aa)
       
  0.862
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
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