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CWC2 protein (Yarrowia lipolytica) - STRING interaction network
"CWC2" - YALI0F29073p in Yarrowia lipolytica
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CWC2YALI0F29073p; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the "nineteen complex" NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre- mRNA intron near the 5’ splice site during the activation and catalytic phases of the s [...] (382 aa)    
Predicted Functional Partners:
PRP46
YALI0E04697p; Involved in pre-mRNA splicing and required for cell cycle progression at G2/M (441 aa)
     
  0.994
ISY1
YALI0D10901p; Involved in pre-mRNA splicing (220 aa)
     
  0.993
SYF1
YALI0D00561p; Involved in pre-mRNA splicing and cell cycle progression (736 aa)
       
  0.993
CLF1
YALI0F18392p; Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity) (676 aa)
       
  0.993
CEF1
YALI0D20086p; Involved in pre-mRNA splicing and cell cycle control (719 aa)
     
  0.991
SLT11
YALI0E33847p; Involved in pre-mRNA splicing. Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA (By similarity) (356 aa)
       
  0.990
XP_501420.1
YALI0C03982p (137 aa)
     
  0.987
XP_500756.1
YALI0B11352p (1111 aa)
     
  0.987
XP_503754.1
YALI0E09889p (601 aa)
     
  0.986
PRP45
YALI0C11715p; Involved in pre-mRNA splicing (568 aa)
     
  0.986
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
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