STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C5DY86_ZYGRCRNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (509 aa)    
Predicted Functional Partners:
C5DQF9_ZYGRC
General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.
   
 0.999
C5DRT8_ZYGRC
ZYRO0B11242p.
    
 0.999
C5DRW3_ZYGRC
ZYRO0B11836p.
    
 0.999
C5DU63_ZYGRC
ZYRO0C14212p.
    
 0.999
C5DUE1_ZYGRC
ZYRO0C16016p.
   
 0.999
C5E0P9_ZYGRC
ZYRO0G14630p.
   
 0.999
C5DQP1_ZYGRC
ZYRO0B01870p.
   
 0.998
C5DWD3_ZYGRC
RNA polymerase II transcription factor B subunit 3; Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA.
    
 0.998
C5DUX5_ZYGRC
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
    
 0.996
C5DRR7_ZYGRC
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
    
 0.985
Your Current Organism:
Zygosaccharomyces rouxii
NCBI taxonomy Id: 559307
Other names: Z. rouxii CBS 732, Zygosaccharomyces rouxii CBS 732
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.