STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
INO80Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1364 aa)    
Predicted Functional Partners:
Q6BIH3_DEBHA
Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family.
    
 0.981
RBV1
RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family.
    
 0.977
Q6BKX2_DEBHA
DEHA2F18194p.
    
 0.970
RVB2
RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family.
   
 0.965
ARP4
Actin-related protein 4; Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes [...]
    
 0.963
Q6BSW7_DEBHA
DEHA2D05412p.
    
 0.947
Q6BKK5_DEBHA
DEHA2F21076p; Belongs to the actin family.
    
 0.935
Q6BW17_DEBHA
DEHA2B15048p.
    
 0.896
B5RT48_DEBHA
DEHA2B05170p.
    
 0.891
Q6BIA3_DEBHA
DEHA2G12320p; Belongs to the actin family.
    
 0.833
Your Current Organism:
Debaryomyces hansenii
NCBI taxonomy Id: 284592
Other names: D. hansenii CBS767, Debaryomyces hansenii CBS767
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.