Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

UTP25

U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2 (719 aa)

Predicted Functional Partners:

XP_458955.2

0.995

XP_459725.2

0.993

XP_002770216.1

0.991

DBP6

0.991

XP_457111.1

0.988

BFR2

0.988

XP_461724.2

0.988

NOP14

0.987

DBP9

0.987

XP_460079.2

0.987

Your Current Organism:

Debaryomyces hansenii

NCBI taxonomy Id: 4959
Other names: ATCC 36239, CBS 767, CCRC 21394, D. hansenii, DBVPG 6050, Debaryomyces hansenii, Debaryomyces sp. ZIM 2431, Debaryomyces tyrocola var. hansenii, IFO 0083, JCM 2101, KCTC 7645, MUCL 30242, NCYC 2572, NRRL Y-10976, NRRL Y-7426, Pichia hansenii, Saccharomyces hansenii, Torulaspora hansenii, UCD 74-86

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... as simple tabular text output:

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TSV: tab separated values - can be opened in Excel

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BFR2	DBP6	XP_456948.2	XP_459782.2	Protein BFR2; Similar to uniprot\|Q06631 Saccharomyces cerevisiae YDR299W BFR2 Essential protein possibly involved in secretion	ATP-dependent RNA helicase DBP6; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs	0.791
BFR2	DBP9	XP_456948.2	XP_460896.1	Protein BFR2; Similar to uniprot\|Q06631 Saccharomyces cerevisiae YDR299W BFR2 Essential protein possibly involved in secretion	ATP-dependent RNA helicase DBP9; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily	0.995
BFR2	NOP14	XP_456948.2	XP_457562.2	Protein BFR2; Similar to uniprot\|Q06631 Saccharomyces cerevisiae YDR299W BFR2 Essential protein possibly involved in secretion	Probable nucleolar complex protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity)	0.992
BFR2	UTP25	XP_456948.2	XP_456795.2	Protein BFR2; Similar to uniprot\|Q06631 Saccharomyces cerevisiae YDR299W BFR2 Essential protein possibly involved in secretion	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2	0.988
BFR2	XP_002770216.1	XP_456948.2	XP_002770216.1	Protein BFR2; Similar to uniprot\|Q06631 Saccharomyces cerevisiae YDR299W BFR2 Essential protein possibly involved in secretion	DEHA2C14300p; Similar to uniprot\|P40079 Saccharomyces cerevisiae YER127W LCP5 Essential protein involved in maturation of 18S rRNA and CA5718\|CaLCP5 Candida albicans	0.996
BFR2	XP_457111.1	XP_456948.2	XP_457111.1	Protein BFR2; Similar to uniprot\|Q06631 Saccharomyces cerevisiae YDR299W BFR2 Essential protein possibly involved in secretion	DEHA2B03366p; Similar to uniprot\|Q12136 Saccharomyces cerevisiae YDL153c SAS10 small ribosomal subunit processosome component	0.979
BFR2	XP_458955.2	XP_456948.2	XP_458955.2	Protein BFR2; Similar to uniprot\|Q06631 Saccharomyces cerevisiae YDR299W BFR2 Essential protein possibly involved in secretion	DEHA2D11264p; Similar to uniprot\|Q06078 Saccharomyces cerevisiae YLR409C UTP21	0.973
BFR2	XP_459725.2	XP_456948.2	XP_459725.2	Protein BFR2; Similar to uniprot\|Q06631 Saccharomyces cerevisiae YDR299W BFR2 Essential protein possibly involved in secretion	DEHA2E09658p; Similar to uniprot\|Q06506 Saccharomyces cerevisiae YPR137W RRP9 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)	0.990
BFR2	XP_460079.2	XP_456948.2	XP_460079.2	Protein BFR2; Similar to uniprot\|Q06631 Saccharomyces cerevisiae YDR299W BFR2 Essential protein possibly involved in secretion	DEHA2E17864p; Similar to uniprot\|Q05946 Saccharomyces cerevisiae YLR222C UTP13 Nucleolar protein	0.996
BFR2	XP_461724.2	XP_456948.2	XP_461724.2	Protein BFR2; Similar to uniprot\|Q06631 Saccharomyces cerevisiae YDR299W BFR2 Essential protein possibly involved in secretion	DEHA2G04092p; Similar to uniprot\|Q04177 Saccharomyces cerevisiae YDR398w UTP5 Nucleolar protein	0.987
DBP6	BFR2	XP_459782.2	XP_456948.2	ATP-dependent RNA helicase DBP6; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs	Protein BFR2; Similar to uniprot\|Q06631 Saccharomyces cerevisiae YDR299W BFR2 Essential protein possibly involved in secretion	0.791
DBP6	DBP9	XP_459782.2	XP_460896.1	ATP-dependent RNA helicase DBP6; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs	ATP-dependent RNA helicase DBP9; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily	0.912
DBP6	NOP14	XP_459782.2	XP_457562.2	ATP-dependent RNA helicase DBP6; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs	Probable nucleolar complex protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity)	0.968
DBP6	UTP25	XP_459782.2	XP_456795.2	ATP-dependent RNA helicase DBP6; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2	0.991
DBP6	XP_002770216.1	XP_459782.2	XP_002770216.1	ATP-dependent RNA helicase DBP6; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs	DEHA2C14300p; Similar to uniprot\|P40079 Saccharomyces cerevisiae YER127W LCP5 Essential protein involved in maturation of 18S rRNA and CA5718\|CaLCP5 Candida albicans	0.661
DBP6	XP_457111.1	XP_459782.2	XP_457111.1	ATP-dependent RNA helicase DBP6; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs	DEHA2B03366p; Similar to uniprot\|Q12136 Saccharomyces cerevisiae YDL153c SAS10 small ribosomal subunit processosome component	0.680
DBP6	XP_458955.2	XP_459782.2	XP_458955.2	ATP-dependent RNA helicase DBP6; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs	DEHA2D11264p; Similar to uniprot\|Q06078 Saccharomyces cerevisiae YLR409C UTP21	0.850
DBP6	XP_459725.2	XP_459782.2	XP_459725.2	ATP-dependent RNA helicase DBP6; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs	DEHA2E09658p; Similar to uniprot\|Q06506 Saccharomyces cerevisiae YPR137W RRP9 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)	0.924
DBP6	XP_460079.2	XP_459782.2	XP_460079.2	ATP-dependent RNA helicase DBP6; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs	DEHA2E17864p; Similar to uniprot\|Q05946 Saccharomyces cerevisiae YLR222C UTP13 Nucleolar protein	0.866
DBP6	XP_461724.2	XP_459782.2	XP_461724.2	ATP-dependent RNA helicase DBP6; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs	DEHA2G04092p; Similar to uniprot\|Q04177 Saccharomyces cerevisiae YDR398w UTP5 Nucleolar protein	0.845

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