STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein- mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck. (529 aa)    
Predicted Functional Partners:
Q6BL44_DEBHA
DEHA2F16522p.
   
 0.997
Q6BPL2_DEBHA
DEHA2E12694p.
    
 
 0.923
B5RUM3_DEBHA
DEHA2F23364p; Belongs to the membrane-bound acyltransferase family.
     
  0.900
Q6BQG7_DEBHA
DEHA2E05390p.
     
  0.900
Q6BXX7_DEBHA
DEHA2A14080p.
   
 0.895
Q6BH89_DEBHA
DEHA2G20460p.
    
 0.870
DYN2
Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity).
    
 0.838
Q6BLB7_DEBHA
DEHA2F14806p.
    
 0.826
Q6BXD0_DEBHA
DEHA2B04092p.
    
 0.805
Q6BSV8_DEBHA
DEHA2D05632p.
    
 0.741
Your Current Organism:
Debaryomyces hansenii
NCBI taxonomy Id: 284592
Other names: D. hansenii CBS767, Debaryomyces hansenii CBS767
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