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LIS1 protein (Debaryomyces hansenii) - STRING interaction network
"LIS1" - Nuclear distribution protein PAC1 in Debaryomyces hansenii
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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LIS1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck (529 aa)    
Predicted Functional Partners:
XP_461077.2
DEHA2F16522p; Similar to uniprot|P36022 Saccharomyces cerevisiae YKR054C DYN1 Cytoplasmic heavy chain dynein (4189 aa)
     
 
  0.974
XP_459553.2
DEHA2E05390p; Weakly similar to uniprot|P36165 Saccharomyces cerevisiae YKR089C STC1 (1025 aa)
         
    0.900
XP_459858.2
DEHA2E12694p; Weakly similar to ca|CA5445|IPF232 Candida albicans IPF232 unknown function (387 aa)
     
 
  0.887
XP_002770295.1
DEHA2D10604p; Weakly similar to uniprot|Q00402 Saccharomyces cerevisiae YDR150W NUM1 nuclear migration protein (3432 aa)
       
 
  0.871
DYN2
Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity) (91 aa)
       
 
  0.842
XP_461855.1
DEHA2G07062p; Similar to CA3844|IPF7945 Candida albicans orf19. 6604, unknown function (276 aa)
           
  0.835
XP_461004.2
DEHA2F14806p; Some similarities with uniprot|P33420 Saccharomyces cerevisiae YPL174C NIP100 Large subunit of the dynactin complex (969 aa)
       
 
  0.833
XP_458209.2
Kinesin-like protein; Similar to uniprot|P28743 Saccharomyces cerevisiae YPL155C KIP2 Kinesin-related motor protein involved in mitotic spindle positioning; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family (668 aa)
     
 
  0.805
XP_002770884.1
DEHA2F23364p; Similar to uniprot|Q08548 Saccharomyces cerevisiae YOR175C Hypothetical ORF; Belongs to the membrane-bound acyltransferase family (603 aa)
         
    0.800
XP_457732.2
DEHA2C01188p; Some similarities with CA3193|IPF3418 Candida albicans IPF3418 unknown function (604 aa)
       
 
  0.792
Your Current Organism:
Debaryomyces hansenii
NCBI taxonomy Id: 4959
Other names: ATCC 36239, CBS 767, CCRC 21394, D. hansenii, DBVPG 6050, Debaryomyces hansenii, Debaryomyces sp. ZIM 2431, Debaryomyces tyrocola var. hansenii, IFO 0083, JCM 2101, KCTC 7645, MUCL 30242, NCYC 2572, NRRL Y-10976, NRRL Y-7426, Pichia hansenii, Saccharomyces hansenii, Torulaspora hansenii, UCD 74-86
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