STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOP58Nucleolar protein 58; Required for pre-18S rRNA processing. May bind microtubules (By similarity); Belongs to the NOP5/NOP56 family. (517 aa)    
Predicted Functional Partners:
Q6BHF2_DEBHA
DEHA2G19074p.
   
 0.999
Q6BIZ9_DEBHA
DEHA2G06314p.
  
0.999
Q6BJ97_DEBHA
DEHA2G04092p.
   
 0.999
SNU13
13 kDa ribonucleoprotein-associated protein; Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
   
 0.999
Q6BNZ1_DEBHA
DEHA2E17864p.
   
 0.999
Q6BPZ5_DEBHA
DEHA2E09658p.
   
 0.999
NOP1
rRNA 2'-O-methyltransferase fibrillarin; S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gl [...]
   
 0.999
Q6BRB9_DEBHA
DEHA2D17578p.
   
 0.999
UTP10
U3 small nucleolar RNA-associated protein 10; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity).
   
 0.999
Q6BJK1_DEBHA
DEHA2G01826p.
   
 
 0.998
Your Current Organism:
Debaryomyces hansenii
NCBI taxonomy Id: 284592
Other names: D. hansenii CBS767, Debaryomyces hansenii CBS767
Server load: low (30%) [HD]