STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIIEStage ii sporulation protein e/serine phosphatase. (819 aa)    
Predicted Functional Partners:
spoIIGA
Sporulation sigma-e factor-processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.935
spoIIR
Stage ii sporulation protein r.
  
   
 0.867
spoIIID
Stage iii sporulation protein d.
  
   
 0.862
spoIIIG
RNA polymerase sigma-g factor, putative; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.860
spoIIP
Stage ii sporulation protein p.
  
   
 0.852
spoIVA
Stage iv sporulation protein a; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.832
spoIIIAA
Stage iii sporulation protein aa.
  
   
 0.811
spoIIIAA-2
Stage iii sporulation protein aa.
  
   
 0.811
spoVT-2
Stage v sporulation protein t, abrb family transcriptional regulator.
 
   
 0.806
spoIIAB
Anti-sigma f factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.802
Your Current Organism:
Heliobacterium modesticaldum
NCBI taxonomy Id: 498761
Other names: H. modesticaldum Ice1, Heliobacterium modesticaldum Ice1, Heliobacterium modesticaldum str. Ice1, Heliobacterium modesticaldum strain Ice1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.