node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argS | guaA | HM1_1065 | HM1_0057 | arginyl-tRNA synthetase. | Gmp synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.968 |
argS | pyrG | HM1_1065 | HM1_1068 | arginyl-tRNA synthetase. | Ctp synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.882 |
argS | rplE | HM1_1065 | HM1_1390 | arginyl-tRNA synthetase. | 50S ribosomal protein l5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.593 |
argS | rplF | HM1_1065 | HM1_1393 | arginyl-tRNA synthetase. | 50S ribosomal protein l6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.534 |
argS | rplJ | HM1_1065 | HM1_1367 | arginyl-tRNA synthetase. | 50S ribosomal protein l10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.658 |
argS | rplM | HM1_1065 | HM1_1413 | arginyl-tRNA synthetase. | 50S ribosomal protein l13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.801 |
argS | rpoB | HM1_1065 | HM1_1370 | arginyl-tRNA synthetase. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.670 |
argS | rpsB | HM1_1065 | HM1_2256 | arginyl-tRNA synthetase. | 30S ribosomal protein s2; Belongs to the universal ribosomal protein uS2 family. | 0.416 |
guaA | argS | HM1_0057 | HM1_1065 | Gmp synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | arginyl-tRNA synthetase. | 0.968 |
guaA | ndk | HM1_0057 | HM1_0677 | Gmp synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.615 |
guaA | pyrG | HM1_0057 | HM1_1068 | Gmp synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Ctp synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.968 |
guaA | rplE | HM1_0057 | HM1_1390 | Gmp synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein l5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.506 |
guaA | rplJ | HM1_0057 | HM1_1367 | Gmp synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein l10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.913 |
guaA | rplM | HM1_0057 | HM1_1413 | Gmp synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein l13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.844 |
guaA | rpoB | HM1_0057 | HM1_1370 | Gmp synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.888 |
guaA | rpsB | HM1_0057 | HM1_2256 | Gmp synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein s2; Belongs to the universal ribosomal protein uS2 family. | 0.750 |
ndk | guaA | HM1_0677 | HM1_0057 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Gmp synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.615 |
ndk | nrdD | HM1_0677 | HM1_2070 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Anaerobic ribonucleoside-triphosphate reductase. | 0.915 |
ndk | pyrG | HM1_0677 | HM1_1068 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ctp synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.937 |
ndk | rplE | HM1_0677 | HM1_1390 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 50S ribosomal protein l5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.726 |