STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase, nad-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (309 aa)    
Predicted Functional Partners:
ttdA
Tartrate dehydratase alpha subunit/fumarate hydratase.
  
 
 0.959
icd
Isocitrate dehydrogenase, nADP-dependent; Also known as citC.
 
 
 0.952
fumB
Fumarate hydratase, beta subunit.
  
 
 0.951
oadA
Oxaloacetate decarboxylase, alpha subunit; Also has gene sym pycB.
    
 0.945
aspB
Aspartate aminotransferase.
  
 0.920
aspB-2
Aspartate aminotransferase; Member of beta-eliminating lyase superfamily, PF01212.
  
 0.920
pckA
Phosphoenolpyruvate carboxykinase; Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
  
 
 0.920
oadA-2
Oxaloacetate decarboxylase, alpha subunit; Also has gene sym pycB.
    
 0.909
gltB
Glutamate synthase [nadph] large chain.
  
 
 0.898
HM1_0807
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Contains alpha, beta and gamma subunits of 2-oxoacid:ferredoxin oxidoreductase, a gene related to pyruvate:ferredoxin (flavodoxin) oxidoreductase. These genes have the gene symbols porA, porB, porG and napF.
  
  
 0.886
Your Current Organism:
Heliobacterium modesticaldum
NCBI taxonomy Id: 498761
Other names: H. modesticaldum Ice1, Heliobacterium modesticaldum Ice1, Heliobacterium modesticaldum str. Ice1, Heliobacterium modesticaldum strain Ice1
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