node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HM1_2087 | carA | HM1_2087 | HM1_1432 | Uracil/xanthine permease. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.797 |
HM1_2087 | carA-2 | HM1_2087 | HM1_2109 | Uracil/xanthine permease. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.797 |
HM1_2087 | carB | HM1_2087 | HM1_1434 | Uracil/xanthine permease. | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.786 |
HM1_2087 | carB-2 | HM1_2087 | HM1_2110 | Uracil/xanthine permease. | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.786 |
HM1_2087 | hydA | HM1_2087 | HM1_2642 | Uracil/xanthine permease. | Dihydropyrimidinase. | 0.809 |
HM1_2087 | pyrB | HM1_2087 | HM1_2107 | Uracil/xanthine permease. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.947 |
HM1_2087 | pyrC | HM1_2087 | HM1_2108 | Uracil/xanthine permease. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.920 |
HM1_2087 | pyrD | HM1_2087 | HM1_2112 | Uracil/xanthine permease. | Dihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.862 |
HM1_2087 | pyrE | HM1_2087 | HM1_0242 | Uracil/xanthine permease. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.896 |
HM1_2087 | pyrR | HM1_2087 | HM1_2105 | Uracil/xanthine permease. | Pyrr bifunctional protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.923 |
carA | HM1_2087 | HM1_1432 | HM1_2087 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Uracil/xanthine permease. | 0.797 |
carA | carA-2 | HM1_1432 | HM1_2109 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.903 |
carA | carB | HM1_1432 | HM1_1434 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.999 |
carA | carB-2 | HM1_1432 | HM1_2110 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.999 |
carA | hydA | HM1_1432 | HM1_2642 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydropyrimidinase. | 0.721 |
carA | pyrB | HM1_1432 | HM1_2107 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.998 |
carA | pyrC | HM1_1432 | HM1_2108 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.984 |
carA | pyrD | HM1_1432 | HM1_2112 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.815 |
carA | pyrE | HM1_1432 | HM1_0242 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.817 |
carA | pyrR | HM1_1432 | HM1_2105 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Pyrr bifunctional protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.758 |