STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pc20g07700Pc20g07700 protein. (788 aa)    
Predicted Functional Partners:
Pc20g01100
Pc20g01100 protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
   
 
0.975
Pc13g04130
Pc13g04130 protein.
   
 
 0.948
Pc21g07230
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
    
 0.942
Pc14g00900
Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
     
0.924
Pc22g20170
Pc22g20170 protein.
     
 0.911
Pc22g04180
Pc22g04180 protein.
     
 0.911
Pc13g08920
Pc13g08920 protein.
     
0.906
Pc16g12270
Histone H3; Belongs to the histone H3 family.
 
 
 0.801
Pc12g07480
Pc12g07480 protein.
   
 
 0.795
Pc22g07100
Pc22g07100 protein.
   
 
 0.795
Your Current Organism:
Penicillium rubens
NCBI taxonomy Id: 500485
Other names: P. rubens Wisconsin 54-1255, Penicillium rubens Wisconsin 54-1255
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.