STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pc22g19330ma2mNitrilase; Nitrilase that hydrolyzes preferentially 4-cyanopyridine. Is also able to hydrolyze some aliphatic nitriles, such as (R,S)- mandelonitrile; Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. (328 aa)    
Predicted Functional Partners:
Pc13g11420
Pc13g11420 protein.
   
 
 0.927
Pc22g08300
NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.922
gdhA
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.922
Pc20g04820
Pc20g04820 protein.
    
 0.914
Pc12g14940
Pc12g14940 protein; Belongs to the glutamine synthetase family.
    
 0.908
Pc20g13560
Pc20g13560 protein; Belongs to the glutamine synthetase family.
    
 0.908
Pc22g03070
Glutamine synthetase.
    
 0.908
Pc13g09350
Pc13g09350 protein.
    
 0.834
chyD
Amidase chyE; Amidase; part of the gene cluster that mediates the biosynthesis of the yellow pigment chrysogine. the NRPS chyA mediates the condensation of anthranilic acid and alanine into the intermediate 2-(2-aminopropanamido)benzoic acid. The remainder of the pathway is highly branched yielding at least 13 chrysogine-related compounds. The malonyl transferase chyE converts 2-(2-aminopropanamido)benzoic acid and 2-(2-aminopropanamido)benzamidine into 2-(2-(2- carboxyacetamido)propanamido)benzoic acid and 3-((1-((2- carbamoylphenyl)amino)-1-oxopropan-2-yl)amino)-3-oxopropanoic acid, [...]
    
 0.830
Pc22g17940
Pc22g17940 protein.
    
 0.830
Your Current Organism:
Penicillium rubens
NCBI taxonomy Id: 500485
Other names: P. rubens Wisconsin 54-1255, Penicillium rubens Wisconsin 54-1255
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