STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAAG_011942-oxoisovalerate dehydrogenase subunit beta. (400 aa)    
Predicted Functional Partners:
PAAG_01310
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
PAAG_02769
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 0.998
PAAG_03330
Dihydrolipoyl dehydrogenase.
 
 0.996
PAAG_08295
Pyruvate dehydrogenase E1 component subunit alpha.
 
 0.990
PAAG_04401
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.976
PAAG_06072
Branched-chain-amino-acid aminotransferase.
  
 0.971
PAAG_00050
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.946
PAAG_08915
Dihydrolipoamide succinyltransferase.
 
 0.927
PAAG_05292
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 0.925
PAAG_00666
Peripheral subunit-binding (PSBD) domain-containing protein.
  
 0.906
Your Current Organism:
Paracoccidioides lutzii
NCBI taxonomy Id: 502779
Other names: P. lutzii Pb01, Paracoccidioides brasiliensis Pb01, Paracoccidioides lutzii Pb01
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.