STRINGSTRING
ung protein (Spirosoma linguale) - STRING interaction network
"ung" - uracil-DNA glycosylase in Spirosoma linguale
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
unguracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (221 aa)    
Predicted Functional Partners:
Slin_4880
DNA polymerase III subunit beta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (379 aa)
   
 
  0.932
Slin_0521
Exodeoxyribonuclease III Xth (254 aa)
     
  0.881
Slin_6029
Nucleoside-diphosphate kinase (139 aa)
     
 
  0.861
thyA
Thymidylate synthase; Provides the sole de novo source of dTMP for DNA biosynthesis (264 aa)
   
 
  0.676
Slin_5983
A/G-specific adenine glycosylase (362 aa)
   
 
  0.655
Slin_0247
ApaG domain-containing protein (128 aa)
              0.647
Slin_0248
O-methyltransferase-like protein (259 aa)
              0.640
Slin_0543
DNA polymerase I (1024 aa)
   
   
  0.637
Slin_1051
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (163 aa)
 
 
  0.583
Slin_6129
Class I and II aminotransferase (390 aa)
       
 
  0.546
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale, S. linguale DSM 74, Spirosoma, Spirosoma linguale, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
Server load: low (9%) [HD]