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Slin_1592 protein (Spirosoma linguale) - STRING interaction network
"Slin_1592" - methylated-DNA--protein-cysteine methyltransferase in Spirosoma linguale
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
Slin_1592methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction- the enzyme is irreversibly inactivated (163 aa)    
Predicted Functional Partners:
Slin_2269
HhH-GPD family protein (207 aa)
 
   
  0.888
queG
Iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (308 aa)
       
  0.838
Slin_0543
DNA polymerase I (1024 aa)
     
 
  0.692
Slin_1593
Twin-arginine translocation pathway signal (336 aa)
              0.657
Slin_1987
RpoD subfamily RNA polymerase sigma-70 subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (287 aa)
     
 
  0.624
Slin_1591
Glucose/sorbosone dehydrogenase (414 aa)
              0.598
Slin_2436
Tyrosine recombinase XerD (305 aa)
 
 
 
  0.549
Slin_3066
Integrase family protein (390 aa)
 
 
 
  0.543
Slin_0098
Integrase family protein (298 aa)
 
 
 
  0.538
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (215 aa)
         
  0.493
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale, S. linguale DSM 74, Spirosoma, Spirosoma linguale, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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