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Slin_1996 protein (Spirosoma linguale) - STRING interaction network
"Slin_1996" - Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase in Spirosoma linguale
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Slin_1996Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase (428 aa)    
Predicted Functional Partners:
Slin_2317
Dihydropteroate synthase (286 aa)
 
  0.996
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (428 aa)
   
  0.946
Slin_1051
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (163 aa)
   
  0.943
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (220 aa)
   
        0.883
Slin_1995
Hypothetical protein (314 aa)
              0.880
folE
GTP cyclohydrolase I (241 aa)
 
  0.842
thyA
Thymidylate synthase; Provides the sole de novo source of dTMP for DNA biosynthesis (264 aa)
     
 
  0.835
Slin_4404
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (159 aa)
   
  0.741
Slin_0785
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (252 aa)
 
   
  0.716
Slin_1744
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (252 aa)
 
   
  0.699
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale, S. linguale DSM 74, Spirosoma, Spirosoma linguale, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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