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Slin_2227 protein (Spirosoma linguale) - STRING interaction network
"Slin_2227" - DNA topoisomerase in Spirosoma linguale
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slin_2227DNA topoisomerase (904 aa)    
Predicted Functional Partners:
Slin_2567
DNA topoisomerase type IIA B domain-containing protein (632 aa)
 
  0.999
gyrB
DNA gyrase subunit beta; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (666 aa)
  0.998
Slin_4880
DNA polymerase III subunit beta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (379 aa)
 
  0.987
Slin_3231
DNA topoisomerase (365 aa)
     
 
  0.867
Slin_2228
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein (310 aa)
   
 
  0.831
Slin_5963
ATP-dependent DNA helicase RecQ (736 aa)
   
  0.779
Slin_6359
Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (826 aa)
   
   
  0.777
argS
arginyl-tRNA synthetase (599 aa)
 
 
  0.769
Slin_0543
DNA polymerase I (1024 aa)
 
 
  0.768
Slin_0436
Hypothetical protein (429 aa)
   
          0.756
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale, S. linguale DSM 74, Spirosoma, Spirosoma linguale, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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