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tsaD protein (Spirosoma linguale) - STRING interaction network
"tsaD" - Glycoprotease family metalloendopeptidase in Spirosoma linguale
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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tsaDGlycoprotease family metalloendopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction (332 aa)    
Predicted Functional Partners:
Slin_6394
Peptidase M22 glycoprotease (235 aa)
 
 
  0.966
crcB
CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity (125 aa)
     
      0.859
Slin_3078
MOSC domain-containing protein (287 aa)
   
        0.838
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (271 aa)
 
   
  0.833
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication (703 aa)
 
   
  0.827
pheT
phenylalanyl-tRNA synthetase subunit beta (814 aa)
 
   
  0.813
secA
Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (1130 aa)
   
  0.810
Slin_5630
seryl-tRNA synthetase (423 aa)
 
 
  0.810
Slin_3028
ABC transporter (226 aa)
 
        0.805
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (439 aa)
 
   
  0.793
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale, S. linguale DSM 74, Spirosoma, Spirosoma linguale, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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