STRINGSTRING
Slin_3231 protein (Spirosoma linguale) - STRING interaction network
"Slin_3231" - DNA topoisomerase in Spirosoma linguale
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slin_3231DNA topoisomerase (365 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit beta; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (666 aa)
     
 
  0.867
Slin_2567
DNA topoisomerase type IIA B domain-containing protein (632 aa)
     
 
  0.867
Slin_2227
DNA topoisomerase (904 aa)
     
 
  0.867
gyrA
DNA gyrase subunit alpha; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (838 aa)
     
 
  0.867
Slin_3230
Hypothetical protein (225 aa)
              0.592
Slin_5292
Short-chain dehydrogenase/reductase SDR (300 aa)
 
          0.576
Slin_0453
Short-chain dehydrogenase/reductase SDR (284 aa)
 
          0.560
Slin_0452
Short-chain dehydrogenase/reductase SDR (287 aa)
 
          0.556
Slin_4034
Short-chain dehydrogenase/reductase SDR (335 aa)
 
          0.527
Slin_5963
ATP-dependent DNA helicase RecQ (736 aa)
     
 
  0.512
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale, S. linguale DSM 74, Spirosoma, Spirosoma linguale, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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