STRINGSTRING
panB protein (Spirosoma linguale) - STRING interaction network
"panB" - 3-methyl-2-oxobutanoate hydroxymethyltransferase in Spirosoma linguale
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (272 aa)    
Predicted Functional Partners:
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (280 aa)
 
 
  0.975
Slin_2608
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (309 aa)
 
   
  0.955
ilvD
Dihydroxy-acid dehydratase (569 aa)
     
 
  0.917
Slin_1829
Dihydroxy-acid dehydratase (568 aa)
     
 
  0.917
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (117 aa)
 
   
  0.913
Slin_1098
Branched-chain amino acid aminotransferase (356 aa)
       
  0.911
Slin_5563
Class IV aminotransferase (283 aa)
       
  0.910
Slin_4400
Pseudouridine synthase (248 aa)
              0.725
Slin_1305
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase (412 aa)
 
        0.670
Slin_4398
Peptidase M23 (475 aa)
              0.594
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale, S. linguale DSM 74, Spirosoma, Spirosoma linguale, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
Server load: low (10%) [HD]