STRINGSTRING
tdk protein (Spirosoma linguale) - STRING interaction network
"tdk" - Thymidine kinase in Spirosoma linguale
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdkThymidine kinase (209 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Provides the sole de novo source of dTMP for DNA biosynthesis (264 aa)
     
 
  0.935
Slin_1927
CMP/dCMP deaminase zinc-binding protein (186 aa)
   
 
  0.915
Slin_3943
Purine nucleoside phosphorylase I; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (271 aa)
         
  0.908
Slin_5163
Transcriptional regulator (774 aa)
              0.859
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates (258 aa)
   
   
    0.836
Slin_5585
5’-nucleotidase (340 aa)
   
   
    0.831
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (357 aa)
   
   
  0.738
Slin_5853
Uracil phosphoribosyltransferase (215 aa)
 
     
  0.657
Slin_0543
DNA polymerase I (1024 aa)
   
 
  0.565
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (428 aa)
 
   
  0.559
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale, S. linguale DSM 74, Spirosoma, Spirosoma linguale, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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