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mfd protein (Spirosoma linguale) - STRING interaction network
"mfd" - Transcription-repair coupling factor in Spirosoma linguale
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second shell of interactors
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filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site (1126 aa)    
Predicted Functional Partners:
Slin_5040
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (971 aa)
 
 
  0.944
Slin_5457
Excinuclease ABC subunit A (997 aa)
 
 
  0.943
Slin_3664
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (832 aa)
   
 
  0.934
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1271 aa)
     
 
  0.861
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (368 aa)
 
   
  0.826
Slin_0543
DNA polymerase I (1024 aa)
   
   
  0.807
priA
Primosomal protein N’; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA (804 aa)
   
   
  0.792
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (203 aa)
   
 
  0.782
Slin_5515
Gliding motility-associated lipoprotein GldJ (420 aa)
 
          0.782
Slin_1303
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA (557 aa)
 
 
  0.758
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale, S. linguale DSM 74, Spirosoma, Spirosoma linguale, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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