Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
Genes that are sometimes fused into single open reading frames.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Type 12 methyltransferase (306 aa)
Predicted Functional Partners:
Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (620 aa)
Chromosome segregation ATPase (1100 aa)
Cell wall hydrolase/autolysin (347 aa)
Hypothetical protein (333 aa)
Hypothetical protein (350 aa)
Response regulator receiver protein (320 aa)
beta-N-acetylhexosaminidase (953 aa)
Glycoside hydrolase (1002 aa)
UspA domain-containing protein (293 aa)
Hypothetical protein (529 aa)
Your Current Organism:
NCBI taxonomy Id: 504472 Other names: S. linguale, S. linguale DSM 74, Spirosoma, Spirosoma linguale, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74