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leuB protein (Spirosoma linguale) - STRING interaction network
"leuB" - 3-isopropylmalate dehydrogenase in Spirosoma linguale
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (358 aa)    
Predicted Functional Partners:
Slin_5902
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (470 aa)
 
  0.999
Slin_5901
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (198 aa)
 
  0.998
Slin_5914
Acetolactate synthase large subunit (588 aa)
 
  0.991
Slin_5897
Pyruvate carboxyltransferase (379 aa)
 
 
  0.989
Slin_5913
Acetolactate synthase small subunit (177 aa)
 
 
  0.982
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (424 aa)
 
 
  0.980
Slin_1010
Pyridoxal-5’-phosphate-dependent protein subunit beta (315 aa)
 
 
  0.974
Slin_5900
Pyruvate carboxyltransferase (506 aa)
 
 
  0.961
ilvD
Dihydroxy-acid dehydratase (569 aa)
 
   
  0.909
Slin_1829
Dihydroxy-acid dehydratase (568 aa)
 
   
  0.872
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale, S. linguale DSM 74, Spirosoma, Spirosoma linguale, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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