STRINGSTRING
proC protein (Spirosoma linguale) - STRING interaction network
"proC" - Pyrroline-5-carboxylate reductase in Spirosoma linguale
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline (267 aa)    
Predicted Functional Partners:
Slin_5523
Delta-1-pyrroline-5-carboxylate dehydrogenase (543 aa)
       
  0.910
Slin_5730
Proline dehydrogenase (363 aa)
     
  0.910
Slin_1478
4-hydroxyproline epimerase; Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha- ketoglutarate. Displays no proline racemase activity (334 aa)
         
  0.909
Slin_3362
Proline-specific peptidase; Releases the N-terminal proline from various substrates (346 aa)
         
    0.900
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate (416 aa)
 
   
  0.893
Slin_0426
Glutamate 5-kinase (359 aa)
 
   
  0.872
Slin_1116
Alanine racemase domain-containing protein (219 aa)
 
   
  0.705
argH
Argininosuccinate lyase (445 aa)
   
   
  0.614
Slin_0407
Argininosuccinate synthase (400 aa)
         
  0.613
Slin_5957
Alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen (378 aa)
   
   
  0.601
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale, S. linguale DSM 74, Spirosoma, Spirosoma linguale, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
Server load: low (8%) [HD]