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nfi protein (Spirosoma linguale) - STRING interaction network
"nfi" - Deoxyribonuclease V in Spirosoma linguale
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nfiDeoxyribonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3’ to a deoxyinosine leaving behind the intact lesion on the nicked DNA (230 aa)    
Predicted Functional Partners:
Slin_6149
Peptidase S41 (513 aa)
              0.659
Slin_6147
Hypothetical protein (30 aa)
              0.619
Slin_6146
Fatty acid hydroxylase (337 aa)
              0.515
Slin_6150
AraC family transcriptional regulator (381 aa)
              0.494
Slin_6151
Hypothetical protein (207 aa)
              0.455
Slin_4880
DNA polymerase III subunit beta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (379 aa)
         
  0.441
Slin_0543
DNA polymerase I (1024 aa)
     
   
  0.437
Slin_5745
Rhomboid family protein (207 aa)
   
        0.408
Slin_5568
Rhomboid family protein (259 aa)
   
        0.408
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (673 aa)
     
 
  0.404
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale, S. linguale DSM 74, Spirosoma, Spirosoma linguale, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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