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gcvH protein (Spirosoma linguale) - STRING interaction network
"gcvH" - Glycine cleavage system protein H in Spirosoma linguale
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (127 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (967 aa)
 
  0.999
gcvT
Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine (364 aa)
 
  0.999
Slin_6035
Dihydrolipoamide dehydrogenase (466 aa)
 
 
  0.997
Slin_5752
Dihydrolipoamide dehydrogenase (466 aa)
 
 
  0.996
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (302 aa)
 
 
  0.988
Slin_4914
Transketolase (801 aa)
   
 
  0.972
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (428 aa)
   
 
  0.969
Slin_1435
Pyridine nucleotide-disulfide oxidoreductase dimerisation subunit (452 aa)
 
 
  0.969
lipB
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (245 aa)
   
  0.964
Slin_5148
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis (79 aa)
     
 
  0.950
Your Current Organism:
Spirosoma linguale
NCBI taxonomy Id: 504472
Other names: S. linguale, S. linguale DSM 74, Spirosoma, Spirosoma linguale, Spirosoma linguale DSM 74, Spirosoma linguale str. DSM 74, Spirosoma linguale strain DSM 74
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