STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde 2,1-aminomutase; Unnamed protein product. (447 aa)    
Predicted Functional Partners:
cu0229
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.999
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.998
cu0234
Thiol-disulfide isomerase/thioredoxin.
  
  
 0.987
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.959
cu0235
Cytochrome c-type biogenesis protein.
  
  
 0.954
cu0225
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.947
cu0160
Polyketide synthase.
    
 0.942
cu0233
Putative phosphoglycerate mutase.
  
    0.921
cu1236
Cytochrome c oxidase subunit III.
      
 0.911
cu1478
Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
      
 0.894
Your Current Organism:
Corynebacterium urealyticum
NCBI taxonomy Id: 504474
Other names: C. urealyticum DSM 7109, Corynebacterium urealyticum ATCC 43042, Corynebacterium urealyticum CIP 103524, Corynebacterium urealyticum DSM 7109, Corynebacterium urealyticum str. DSM 7109, Corynebacterium urealyticum strain DSM 7109
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