STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smcSMC domain-containing protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1074 aa)    
Predicted Functional Partners:
AGK04164.1
Hypothetical protein.
  
 
 0.913
AGK05662.1
Chromosome segregation and condensation protein ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
 
 
 
 0.846
AGK04137.1
CheA signal transduction histidine kinase; COG0643 Chemotaxis protein histidine kinase and related kinases.
   
 0.772
AGK06248.1
COG5401 Spore germination protein.
   
   0.766
AGK03977.1
Competence/damage-inducible protein CinA; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family.
    
  0.749
AGK04140.1
COG3300 MHYT domain (predicted integral membrane sensor domain).
  
  0.734
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  0.700
AGK05234.1
GAF sensor-containing diguanylate cyclase/phosphodiesterase; COG2203 FOG: GAF domain.
   
 
  0.686
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
 
  0.686
AGK06249.1
Cell wall hydrolase/autolysin; COG0860 N-acetylmuramoyl-L-alanine amidase.
  
    0.677
Your Current Organism:
Meiothermus ruber
NCBI taxonomy Id: 504728
Other names: M. ruber DSM 1279, Meiothermus ruber ATCC 35948, Meiothermus ruber DSM 1279
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.