STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cseg_2668PFAM: Aldehyde Dehydrogenase; KEGG: ccs:CCNA_01274 piperideine-6-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa)    
Predicted Functional Partners:
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.945
Cseg_0581
PFAM: Aldehyde Dehydrogenase; KEGG: ccs:CCNA_00424 aldehyde dehydrogenase.
  
  
 
0.918
Cseg_1190
KEGG: ccs:CCNA_02601 glutathione-dependent formaldehyde dehydrogenase; TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.915
Cseg_1654
TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; KEGG: ccs:CCNA_01416 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; Belongs to the HIBADH-related family.
  
 
 0.915
Cseg_3013
KEGG: ccs:CCNA_02601 glutathione-dependent formaldehyde dehydrogenase; TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.915
Cseg_3521
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ccs:CCNA_03124 NAD/mycothiol-dependent formaldehyde dehydrogenase.
 
 0.915
Cseg_2629
PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: ccs:CCNA_01645 3-hydroxyisobutyrate dehydrogenase.
  
 
 0.914
Cseg_3376
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rhi:NGR_c27350 NADP-dependent alcohol dehydrogenase C.
  
 
 0.911
Cseg_3464
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: cak:Caul_2461 alcohol dehydrogenase.
 
 
 0.911
Cseg_2930
KEGG: ccs:CCNA_02357 malonate-semialdehyde dehydrogenase (acetylating)/methylmalonate-semialdehyde dehydrogenase (acylating); TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase.
  
  
 
0.909
Your Current Organism:
Caulobacter segnis
NCBI taxonomy Id: 509190
Other names: C. segnis ATCC 21756, Caulobacter segnis ATCC 21756, Caulobacter segnis DSM 7131, Caulobacter segnis IFO 13240, Caulobacter segnis str. ATCC 21756, Caulobacter segnis strain ATCC 21756
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