STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_15945Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (277 aa)    
Predicted Functional Partners:
NECAME_13711
Gamma-aminobutyric acid receptor-associated protein.
  
 0.999
NECAME_16975
Putative gamma-aminobutyric acid receptor-associated protein.
   
 0.982
NECAME_05912
Kinase domain protein; Belongs to the protein kinase superfamily.
   
 
 0.956
NECAME_05913
Uncharacterized protein.
   
 
 0.956
NECAME_08329
Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.
  
  
0.929
NECAME_12737
Autophagy-related protein 3.
   
 
 0.818
NECAME_08056
Kinase domain protein; Belongs to the protein kinase superfamily.
   
 
 0.796
NECAME_11138
WD domain, G-beta repeat protein.
   
 
 0.783
NECAME_10568
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.
   
 
 0.744
NECAME_10905
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
   
  
 0.732
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.