STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECAME_15950Signal peptidase I. (181 aa)    
Predicted Functional Partners:
NECAME_16687
Uncharacterized protein.
   
 0.914
NECAME_14011
Signal peptidase complex subunit 3.
   
 0.905
NECAME_01509
Uncharacterized protein.
   
 0.895
NECAME_15693
WD domain, G-beta repeat protein.
    
 0.890
NECAME_18757
Uncharacterized protein.
 
      0.885
NECAME_15948
Uncharacterized protein.
 
      0.884
NECAME_15949
Sec7_N domain-containing protein.
 
      0.882
NECAME_18690
Uncharacterized protein.
    
 0.804
NECAME_10399
Uncharacterized protein.
    
 0.804
NECAME_19408
Uncharacterized protein.
   
 0.770
Your Current Organism:
Necator americanus
NCBI taxonomy Id: 51031
Other names: N. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.