NECAME_15126 protein (Necator americanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NECAME_15126

Uncharacterized protein. (111 aa)

Predicted Functional Partners:

NECAME_14003

0.740

NECAME_12660

0.740

NECAME_19187

0.668

NECAME_17492

0.668

NECAME_17491

0.668

NECAME_05853

0.633

NECAME_01049

0.574

NECAME_11248

0.487

NECAME_12948

0.478

NECAME_16084

0.478

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_01049	NECAME_12948	W2SMK6	W2SY66	Electron transfer flavoprotein subunit beta.	FAD binding domain protein.	0.593
NECAME_01049	NECAME_15126	W2SMK6	W2SJF9	Electron transfer flavoprotein subunit beta.	Uncharacterized protein.	0.574
NECAME_01049	NECAME_16084	W2SMK6	W2U0H7	Electron transfer flavoprotein subunit beta.	FAD binding domain protein.	0.593
NECAME_05853	NECAME_11248	W2TXT3	W2T525	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.	UTP--glucose-1-phosphate uridylyltransferase.	0.995
NECAME_05853	NECAME_12660	W2TXT3	W2SZ68	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	0.501
NECAME_05853	NECAME_14003	W2TXT3	W2STJ7	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.	Glucosamine-6-phosphate isomerase.	0.735
NECAME_05853	NECAME_15126	W2TXT3	W2SJF9	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.	Uncharacterized protein.	0.633
NECAME_05853	NECAME_17491	W2TXT3	W2TQP6	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.	Amidohydro-rel domain-containing protein.	0.963
NECAME_05853	NECAME_17492	W2TXT3	W2TNK7	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.	Calponin-homology (CH) domain-containing protein.	0.645
NECAME_05853	NECAME_19187	W2TXT3	W2SQ65	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.	Uncharacterized protein.	0.645
NECAME_11248	NECAME_05853	W2T525	W2TXT3	UTP--glucose-1-phosphate uridylyltransferase.	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.	0.995
NECAME_11248	NECAME_14003	W2T525	W2STJ7	UTP--glucose-1-phosphate uridylyltransferase.	Glucosamine-6-phosphate isomerase.	0.631
NECAME_11248	NECAME_15126	W2T525	W2SJF9	UTP--glucose-1-phosphate uridylyltransferase.	Uncharacterized protein.	0.487
NECAME_12660	NECAME_05853	W2SZ68	W2TXT3	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.	0.501
NECAME_12660	NECAME_15126	W2SZ68	W2SJF9	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	Uncharacterized protein.	0.740
NECAME_12660	NECAME_17491	W2SZ68	W2TQP6	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	Amidohydro-rel domain-containing protein.	0.909
NECAME_12660	NECAME_17492	W2SZ68	W2TNK7	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	Calponin-homology (CH) domain-containing protein.	0.909
NECAME_12660	NECAME_19187	W2SZ68	W2SQ65	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	Uncharacterized protein.	0.909
NECAME_12948	NECAME_01049	W2SY66	W2SMK6	FAD binding domain protein.	Electron transfer flavoprotein subunit beta.	0.593
NECAME_12948	NECAME_15126	W2SY66	W2SJF9	FAD binding domain protein.	Uncharacterized protein.	0.478